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[DOI] [Google Scholar] 53.Cancello R

Mazdutide achieved its primary endpoint and all key secondary endpoints in the first Phase III clinical study (GLORY-1) conducted in overweight or obese adults in China

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F prausnitzii abundance doubled following the administration of a GLP-1 receptor agonist, leading researchers to believe that this may be one of the ways the medication works to improve glucose tolerance

2024 Meta-Analysis Indicates That GLP-1RAs Reduce Adverse CV Events A 2024 Meta-analysis of 13 multiple cardiovascular outcome trials has documented that GLP1-RA therapy significantly reduces the risk of major adverse cardiovascular events (MACEs), all-cause mortality, CV mortality, stroke, risk for coronary revascularization, and composite adverse kidney outcomes in both sexes, regardless of a patient's history of cardiovascular disease, BMI or eGFR (Rivera et al, 2024)