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Further, reductions in dorsolateral PFC BOLD response to food cues correlate with drops in fasting levels of ghrelin [44]

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Relationship with Clinical Phenotype and Metabolic Comorbidities Metabolic comorbidities may influence the clinical presentation of PD, leading to an earlier onset of cognitive impairment, a greater burden of axial symptoms, and a reduced response to dopaminergic medication [62]

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