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This first part of TM5 is also involved in glucagon affinity in GCGR, with several mutations showing some effect on binding (Siu et al., 2013)

[DOI] [PMC free article] [PubMed] [Google Scholar] 85.Coskun T, et al

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These findings highlight the importance of understanding the intricate interplay between DPP-4, bone metabolism, and systemic health [9, 11,12,13,14,15,16,17,18,19]

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