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This in-depth review article explores the mechanisms behind the ...

DPP-4 inhibitors were introduced for the treatment of type 2 diabetes in 2006

Robert Kushner, who helped bring them to market, breaks down how they actually work, who benefits most, and why they're a long-term commitment rather than a quick fix.

GLP-1 receptor agonist injections remain the most effective weight-loss medications available, with real-world data showing sustained results when paired with lifestyle changes

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and promotion of muscle mitochondria biogenesis.The potential for GLP-1R agonists to improve muscle function and architecture underscores the need for large randomized controlled, clinically comparative trials of GLP-1R agonists in patients with IIM.