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More to learn about the effects of semaglutide (GLP-1 RA) Science is still learning about how semaglutide (GLP-1 RA) drugs affect the body, including how they may impact the way you respond to food

While BW reduction likely contributes to improvements in conditions, such as hepatic steatosis or sleep apnea, GLP-1 RAs may also exert direct disease-specific effects, particularly through central mechanisms implicated in neurodegeneration and addiction [39]

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Sjstrm L, Narbro K, Sjstrm CD, Karason K, Larsson B, Wedel H, et al

10.1210/jendso/bvac150.808 2 AdministrationU

Previous work has noted that self-report data remain a valid and useful measure in many contexts 31 , but downward biases in self-reported weight are common 32 and may be influenced by factors including health awareness, culture and social norms 33
