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These individuals appear to have a puzzling condition called GLP-1 resistance, where their bodies produce higher levels of the hormone targeted by these drugsbut dont respond to it properly.

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GLP-1 medications carry high price tags due to manufacturing complexity, patent protections, and limited competition

Biochemical and Biophysical Research Communications, 613, 159-165

Glucagon-like peptide-1 (GLP-1) and serotonin play critical roles in energy balance regulation
