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Potential implications of the FDA approval of semaglutide for overweight and obese adults in the United States

Wegovy and Mounjaro are both safe if you always use either medication exactly as instructed by your treatment provider

Epidemiology 33 , 563571 (2022)

While bile changes can affect medication absorption, many post-cholecystectomy patients achieve excellent weight loss with semaglutide, especially when using the injectable form, which bypasses intestinal absorption issues

Intra-articular administration of liraglutide mitigates synovial tissue alteration and cartilage degradation in preclinical osteoarthritis models

Spencers approach is instructive: I prescribe these medications regularly, but I always emphasize that they work best as part of comprehensive care