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Patient-derived human islets from male and female cadaveric donors were 3D-cultured in solubilised extracellular matrix gel in co-culture with the same donor PBMCs, and incubated with cytokines (IL-1, TNF-, IFN-) for 2448 h in the presence of vehicle or increasing concentrations of the CB1R blocker JD-5037

According to PharmaTrac data., Mounjaro launched in March last year, added Rs.105 crore in December, taking its total sales to Rs.600 crore in sales, reflecting rapid uptake despite hardly any insurance coverage and outofpocket affordability constraints.

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