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However, both medications independently lower appetite and alter how the gastrointestinal tract processes food

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And the honest truth is that the emerging science a 2026 systematic review, a growing body of pharmacovigilance data, and the lived experience of thousands of people is confirming something that anyone who has lived through food dysfunction already knows: You cannot shortcut the reward system without consequences to the full emotional landscape

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Singh S, Dulai PS, Zarrinpar A, Ramamoorthy S, Sandborn WJ (2017) Obesity in IBD: epidemiology, pathogenesis, disease course and treatment outcomes