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Safety Considerations and Future Outlook As with all pharmacotherapy for obesity and T2D, establishing cardiovascular safety and demonstrating improvements in meaningful clinical outcomes will be essential, particularly as cardiovascular outcome trials have not yet been completed with multi-agonists (although data are expected soon for tirzepatide: SURPASS-CVOT [T2D] in 2025

Challenges and future prospects of targeting myostatin/activin A signaling to treat diseases of muscle loss and netabolic dysfunction

503B pharmacy standards), clinical support infrastructure, and geographic distribution

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Without insurance, the list prices for each are as follows: Mounjaro: $1,069.08/month Wegovy: $1,349.02/month That may not be an enormous disparity, and each company has different savings programs for certain groups, which may further reduce costs