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For autoimmune patients whose conditions have a gut component, which includes most of them to varying degrees, the local gut effects of GLP-1 receptor activation may contribute to systemic immune improvement

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The doctor may need to consider prior dose, side effects, current appetite, blood sugar status, constipation or nausea history, hydration, weight trajectory, lab markers, cost, access, and maintenance goals

More than a decade of research now shows that TCF7L2, a transcription factor regulator, impacts the production of insulin in the pancreas

2003;284:R1427R1435

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