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Exploring new therapeutic pathways with cautious optimism - By Buonsenso and the Kids

GLP-1 has proven its mettle as a well-tolerated, highly effective and sustainable weight loss injection, but many still misunderstand how it works.

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A network meta-analysis of nine randomized controlled trials found that once-weekly semaglutide showed the largest estimated weight-loss effect among GLP-1 receptor agonists tested in adults with mental illness and obesity or related metabolic risk

Few medications have had such a meteoric rise as semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound), the GLP-1-based treatments for obesity t...