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Third, immortal time bias may artificially inflate apparent protective effects if the period between cohort entry and treatment initiation is misclassified as exposed time

-Real-world data: some associations between GLP-1RA use and lower risk of hospitalisation for substance use in older adults with T2D

Should You Stay on GLP-1 Long-Term or Plan to Stop

Lean muscle mass: Weight loss with medicines of this class can include some loss of lean muscle mass alongside fat mass

Assuming it is safe and effective, retatrutide has the potential to transform how obesity is addressed across the globe, particularly for those who havent succeeded with diet, exercise, or alternative pharmaceuticals

What About the Skin and Face After Weight Loss While GLP-1 medications can reduce body fat, they may also contribute to facial volume loss or skin laxity if weight comes off quickly