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This is where some individuals begin noticing subtle changes

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K., GlucoseDependent Insulinotropic Polypeptide: A Bifunctional GlucoseDependent Regulator of Glucagon and Insulin Secretion in Humans, Diabetes 60, no

a classical experiment involving damaging a small part of the brain (In technical jargon, a bilateral Ventromedial hypothalamic lesion) caused rats to become morbidly obese (Pictured to the right)