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The trial randomised participants to subcutaneous retatrutide at doses of 1 mg, 4 mg, 8 mg and 12 mg or placebo, administered once weekly for a total of 48 weeks

Mechanistically, GLP1RAs improve cardiac function by enhancing contractility and reducing myocardial injury 14,15,16 , exert vasodilatory and endothelial-protective effects, and display anti-inflammatory and anti-fibrotic actions that may limit adverse remodeling in heart failure (HF) 17

Theyre an aid to make lifestyle modification more achievable for people who have struggled with obesity

Semaglutide is a game-changer in the field of medical weight loss, offering hope to individuals struggling to lose weight through traditional methods

GLP-1s aren't increasing penis sizes worldwide

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