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After a mean duration of semaglutide treatment of 7.3 5.8 months using a mean last dose of 1.1 0.2 mg/week, the mean excess weight loss was 28 28% (0 to 70%) while the BMI z-score decreased by 0.41 [131]

Weight loss itself lowers inflammatory cytokines, but Tirzepatide also appears to reduce systemic inflammationhelping quiet the low-grade inflammation that can keep tissues from healing

A modern obesity treatment plan isn't just about the medication

Your risk of getting low blood sugar may be higher if you use Trulicity with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin

Most Recent Byetta Side Effects Information As of October 2025, the most common Byetta side effects reported to the FDA were hyperglycemia, weight loss, low blood sugar and gastrointestinal upset (nausea, vomiting and diarrhea)