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The decision to combine metformin with GLP-1 therapy depends on individual metabolic factors, kidney function, and weight loss goals

However, in subjects with or without pre-existing HF symptoms, linagliptin and sitagliptin had a neutral effect

Among participants in the semaglutide study who smoked cigarettes, those receiving the medication reported a steeper drop in daily cigarette use compared to those on placebo

In the SURMOUNT-1 trial, tirzepatide 15 mg produced 22.5% weight loss at 72 weeks

Arch Gen Psychiatry 67(3):220229

#GLP1 #Obesity #Diabetes #SexDifferences Great insight, Scott, Its striking how little we still know about sex differences in the effects of GLP-1 receptor agonists, especially given their growing role in the treatment of diabetes and obesity
