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The authors connect this to something known as the rate hypothesis in addiction research: the faster a substance hits the brain, the stronger and more rewarding it feels

Initiators of GLP1-RAs, SGLT2i, or DPP4i aged60 years with type 2 diabetes and without cognitive impairment were compared pairwise in three separate analyses

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Additionally, liraglutide shifted polarized macrophage phenotype in vitro from the pro-inflammatory M1 phenotype to the M2 anti-inflammatory phenotype