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The researchers also found that the reduction in LFC was related to the amount of fat in the liver at the beginning of the study, as well as reductions in VAT, ASAT, and body weight in the tirzepatide groups

Some individuals maintain 2040% of their initial weight loss even after stopping, particularly if they've built durable lifestyle changes during their treatment window

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1 3 Tirzepatide as Compared with Semaglutide for the Treatment of Obesity Published May 11, 2025 DOI: 10.1056/NEJMoa2416394 4 IQVIA social media listening study on AOMs between June 2024 and May 2025 where 11,431 conversations were sampled from the US and UK
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While some previous studies reported I values or mentioned heterogeneity, they lacked robust sensitivity testing across all outcomes
