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EVOLUTION OF GLP-1 THERAPY Despite the considerable momentum to acclaim GLP-1 as a preferred first-line injection therapy for the treatment of type 2 diabetes, other routes of administration than injections have long been pursued

An obesity medicine specialist breaks down the reactions you can encounter with GLP-1 drugs

They bind GLP-1 receptors, stimulating insulin release, reducing glucagon secretion, and promoting fullness, all of which help regulate blood sugar and support weight loss

However, most trials have been small and lacked placebo controls, so large randomized trials are still needed

Its the active ingredient in Wegovy (approved specifically for weight loss) and Ozempic (approved for Type 2 diabetes, widely used off-label for weight management)

These systems aim to optimize treatment outcomes by increasing the bioavailability, reducing side effects, and facilitating controlled drug release