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had a run-in period before randomization and withdrew all OADs excluding metformin at the start of the run-in phase ( Table 1 Outlines of the included studies
The partial AUCs and associated daily dose equivalents vary over the weekly dosing interval according to the plasma concentration profile
Ponirakis G, Abdul-Ghani MA, Jayyousi A, Zirie MA, Qazi M, Almuhannadi H, Petropoulos IN, Khan A, Gad H, Migahid O, Megahed A, Al-Mohannadi S, AlMarri F, Al-Khayat F, Mahfoud Z, Al Hamad H, Ramadan M, DeFronzo R, Malik RA (2021) Painful diabetic neuropathy is associated with increased nerve regeneration in patients with type 2 diabetes undergoing intensive glycemic control
The Journal of Physiology
Consequently, these patients require a lower food intake which often leads to weight loss
Gastroenterology 130 (1), 4454
