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Ahmann AJ, Capehorn M, Charpentier G, Dotta F, Henkel E, Lingvay I, Holst AG, Annett MP, Aroda VR

It slows down gastric emptying, meaning food stays in your stomach longer, prolonging the feeling of satiety

Experiments indicate that it acts through the BMP2/Smad/RUNX2 pathway [21] and long intergenic non-coding RNA 968 (LINC00968)/micro-RNA-3658 (miR-3658)/RUNX2 pathway [27]

Appetite & Craving Control Promotes a feeling of fullness and satisfaction, making it easier to reduce overeating and control portions

John Eng, an endocrinologist at the Veterans Affairs Medical Center in the Bronx, was investigating the biochemical composition of Gila monster venomous saliva when he isolated a peptide he named exendin-4

Possible effects on energy balance and body composition: Some data suggest modest improvements in energy expenditure and preferential loss of fat mass versus lean mass, but appetite suppression is the dominant driver of weight loss