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Constipation can be managed by getting enough fiber in your diet and drinking plenty of water

Am J Physiol Renal Physiol (2010) 298(1):F17786

Mean change from baseline for body weight on Day 20 at a dose of 0.2 mg SAR425899 was 3.87% (0.87)
Sleep, stress, and life Poor sleep increases hunger hormones (ghrelin) and reduces fullness hormones (GLP-1, CCK, PYY)

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[19] [18] Mirtazapine, a tetracyclic antidepressant, is well known for causing significant weight gain and increased appetite, which can complicate diabetes management and weight loss goals
