naturally occurring glp-1 agonists Unlocking the multifaceted roles of GLP-1: Physiological functions and therapeutic potential The Multifaceted Nature of GLP-1:

As of 2022, GLP-1RAs have been recommended as first-line treatments, along with SGLT-2 inhibitors, for patients with T2DM and cardiovascular disease in American Diabetes Associations Standards of Medical Care in Diabetes (248, 249)

Side Effects Phentermine side effects: Increased heart rate Insomnia Dry mouth Anxiety GLP-1 side effects: Nausea Vomiting Digestive discomfort Mild fatigue Phentermine can feel more intense due to its stimulant nature

[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Marx N, Federici M, Schtt K, et al

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The effect of glucagon like peptide-1 receptor agonist on behavioral despair and anxiety-like behavior in ovariectomized rats: modulation of BDNF/CREB, Nrf2 and lipocalin 2