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Key Takeaway: GLP-1 medications are designed with a long half-life to provide consistent appetite suppression over seven days

not all participants achieved significant weight loss

10.1021/acs.jproteome.7b00802 3 BelzerC.de VosW

The starting dose of insulin detemir was 10 units/day and the mean dose at the end of the 26-week randomized period was 39 units/day

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For example, a 72-week phase II trial involving 320 patients with MASH, reported MASH resolution rates of up to 59% at the highest dose of 0.4 mg daily as compared to 17% in the placebo group
