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Research guide to cagrilintide (CagriSema) - long-acting amylin analog achieving 20.4% weight loss in combination with semaglutide in REDEFINE Phase 3 trials.

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The data supports continued use in: Type 2 diabetes Obesity and metabolic syndrome Patients with cardiometabolic risk factors Reasonable caution is still appropriate in individuals with: Active pancreatitis Recurrent idiopathic pancreatitis Severe hypertriglyceridemia until corrected