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In particular, the gutbrain axis has garnered attention as a bidirectional system capable of regulating mood, motivation, and reward-seeking behavior via endocrine, neural, and immune pathways [3,4]

[DOI] [PMC free article] [PubMed] [Google Scholar] 85.Huang Y, et al

Studies comparing these two approaches have found significant differences: Canadian patients with type 2 diabetes experienced greater reductions in HbA1c levels and more substantial weight loss with tirzepatide compared to single-target GLP-1 medications

Frequently Asked Questions Q: How much weight can I expect to lose with GLP-1 medications

Many patients tell us the biggest relief is mental

Nowadays, incretin mimetic drugs such as glucagon-like peptide 1 receptor (GLP-1R) agonists have gained extensive popularity for the treatment of diabetes and obesity
