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The most significant is the restricted number of included studies

Weight loss and nutritional deficiencies in severe cases

This in turn reduces the amount of insulin the body needs, ultimately resulting in reduced hyperglycemia and improved control of glucose levels

[DOI] [PubMed] [Google Scholar] 173.Neeland IJ, Linge J, Birkenfeld AL

they can be profoundly debilitating, requiring extensive medical intervention and causing significant long-term health issues

Neurochemically mediated sexual side effects typically resolve within one to two months after discontinuation, as semaglutide clears the system and brain chemistry recalibrates