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Future studies should prioritize early PsA populations, ideally using stratified designs that incorporate metabolic profiling, to fully elucidate the dual immunomodulatory and metabolic potential of GLP-1RAs in altering disease trajectory

Data are presented as mean values with error bars indicating 95% confidence intervals

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Role of orexin receptors in obesity: from cellular to behavioral evidence

These hormones regulate blood glucose levels and appetite by enhancing insulin secretion, suppressing glucagon release, and slowing gastric emptying