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A 2022 systematic review found that once-weekly semaglutide 1 mg significantly improved glycemic control, lowering HbA1c by about 1.7 percentage points compared with placebo, while also reducing fasting glucose

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In a 2021 study, it was found that those who injected Semaglutide/GLP-1 saw better weight-loss results than those who took other approved weight-loss medications, including Phentermine