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Moreover, the development of DR after 6 years was 7.7% for the MIT group and 32.0% for the CIT group in the primary-prevention cohort (no microvascular disease at baseline) (P = 0.039), and progression of DR occurred in 19.2% of the MIT group and 44.0% of the CIT group in the secondary-intervention cohort (microvascular disease at baseline) (P = 0.049)

Hydration becomes even more critical for this population, as exercise-induced fluid losses compound the dehydration risk from GI side effects

2019;42(7):e1112

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