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PIONEER 1: Randomized Clinical Trial of Oral Semaglutide Versus Placebo in Patients With Type 2 Diabetes

Another Novo Nordisk drug that contains semaglutide, Wegovy, is prescribed primarily for weight management and earned an additional $635-million last year

GLP-1 medications work on the brains reward center, known as the mesolimbic system

For many people, the proven health benefits of GLP-1s outweigh the potential downsides

23 The other is made right inside the brain, mostly in preproglucagon neurons of the caudal hindbrain, specifically the nucleus tractus solitarius (NTS) and the adjacent intermediate reticular nucleus

Peptides can be natural or synthetic and are represented by many different drugs
