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F., Orskov C., and Holst J
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However, in partial responders or those unable to escalate dose, future strategies may involve agents such as peripherally acting cannabinoid type 1 receptor antagonists, FGF21 analogs, amylin mimetics, or emerging triple agonists like retatrutide, which target GLP-1, GIP, and glucagon receptors simultaneously
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Differential Processing of Proglucagon by the Subtilisin-Like Prohormone Convertases PC2 and PC3 to Generate Either Glucagon or Glucagon-Like Peptide
