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Description
Concerns about pancreatitis have emerged since GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and liraglutide (Victoza) became widely prescribed for type 2 diabetes and weight management
Meanwhile, GLP-1R was detected in human coronary artery endothelial cells and umbilical vein endothelial cells, and GLP-1 or exendin-4 treatment led to nitric oxide production in both cell types, indicative of GLP-1 involvement in the vasculature (Nystrom et al., 2004
Eur J Endocrinol 174(6):775784
Highlights of Prescribing Information: Xenical (orlistat) Capsules, for oral use
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