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Lancet (London, England) 2017;390(10113):26272642

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These direct effects are further supported by human studies demonstrating the wide expression of GLP-1 receptors in the proximal tubules, juxtaglomerular cells, hilar and intralobular arteries, and preglomerular vascular smooth muscle cells [49]

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The semaglutide calculator accounts for escalation protocols automatically
