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Description
Wegovy is FDA-approved for chronic weight management in adults with obesity or with overweight and a weight-related health condition (e.g

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however, uncertainty persists due to heterogeneity in study design, outcome definitions, and follow-up duration

UK product information advises monitoring for depression or suicidal thoughts despite no proven causal association

Leptin activates TRPC channels to depolarize LepR-expressing neurons in the ventral premammillary nucleus (PMV) and POMC neurons in the ARC [143, 144]

The study protocol is available in the International Prospective Register of Systematic Reviews (registration No
