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Most people notice reduced appetite within the first 12 weeks

Comparative analyses indicate tirzepatide often produces faster, larger weight loss than semaglutide in many patients

Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial

Most patients notice reduced hunger between weeks 1 and 3, with clinical data showing average weight loss acceleration around week 4

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10.1523/JNEUROSCI.1607-04.2004 [DOI] [PMC free article] [PubMed] [Google Scholar] Adams, J
