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Never discontinue GLP-1 medication without medical guidance, as abrupt cessation may worsen glycaemic control or cause weight regain

This contributes to eating more at each sitting and feeling hungry sooner between meals

HRT directly addresses this by maintaining bone density

Women using oral hormonal contraceptives should be aware that Zepbound may reduce their effectiveness, requiring alternative or backup contraception during initiation and dose escalation periods

If tirzepatide proves ineffective, your provider may recommend trying semaglutide instead, as some people respond better to one medication than the other

This is temporary