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[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Stevens P.E., Ahmed S.B., Carrero J.J., Foster B., Francis A., Hall R.K., Herrington G., Hill G., Inker L.A., Kazancolu R., et al

It is currently under FDA review and is not yet commercially available

TRIUMPH is Eli Lilly's Phase 3 clinical programme for Retatrutide
Specifically, GLP-1R engagement may alleviate endoplasmic reticulum (ER) stress, suppress microglial overactivation, and attenuate the release of pro-inflammatory cytokines and hippocampal neuronal apoptosis

27-30 GLP-1RAs were also associated with reduced hazard in exudative AMD compared with insulin, aspirin, and statins
GLP-1 receptor agonists are not currently recommended for use during breastfeeding due to insufficient safety data in lactating populations
