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Science 359 , 10421046 (2018)

Zhang et al., 2015

GLP-1 receptor agonists reduce energy intake by up to roughly 40%, according to a 2025 review of the evidence, and they do it through three overlapping pathways: appetite suppression, delayed gastric emptying, and altered nutrient absorption

LSM values were also significantly associated to liver fat content measured with MRI-PDFF

Tirzepatide, when combined with a healthy diet and physical activity, can result in considerable weight loss, up to 20%