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Absorption Concerns of Other Medications Wegovys mechanism involves slowing gastric emptying

Weeks 17+: 12.5mg or 15mg once weekly (maximum)

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Because the Phase 2 trial used a dose-escalation protocol starting participants at a lower dose before gradually increasing the weight loss observed at one month reflects early-stage, titration-phase treatment rather than the drug's full therapeutic effect

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One recent propensity-matched study even observed a slightly lower lifetime pancreatitis risk in GLP-1RA users (0.3 % vs 0.4 %), possibly reflecting overall better diabetes control [35]
