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Furthermore, leptin receptor-deficient mice, a mouse model of obesity and diabetes, and people with endogenous glucagon deficiency (pancreatectomised individuals) treated with glucagon antisense oligonucleotide have increased hepatic fat [52, 53]

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Wegovy (up to 7.2 mg) is for weight management
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[4] [5] The three primary subcutaneous injection sites used for comparable licensed therapies (such as semaglutide and tirzepatide, as described in their UK Summary of Product Characteristics) are: Abdomen the area around the stomach, avoiding the area immediately around the navel Front (anterolateral) thigh the outer-front portion of the upper thigh Upper arms the outer area of the upper arm, typically requiring assistance from another person for self-administration The abdomen is generally considered the most accessible and commonly used site, as it offers a relatively large surface area of subcutaneous fat and is straightforward to self-administer
