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Currently, GLP-1RAs have been marketed mainly as liraglutide, exendin-4, albiglutide, dulaglutide and semaglutide (Meier, 2012
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Several small clinical studies and case reports have documented significant reductions in hyperphagia and weight loss in PWS patients treated with GLP-1 agonists, though large-scale randomized trials are still limited
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Recent advances in biomaterial science have also enabled the incorporation of Ex-4 into novel scaffold systems using electrospinning methods
