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It is a mix of behavior and biology, but I would say it leans heavily toward biology. When you lose weight, the body employs a number of defense mechanisms

GLP-1s have rapidly become first-line therapy for many patients because they directly address the underlying driver: excess fat deposition in the liver

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Aside from the metabolic role of GLP-1RAs, which aids in the relief of PCOS symptoms, there is also the possibility of direct involvement in reproductive health in PCOS, including its role in the hypothalamic-gonadal axis, menstrual irregularity, ovulation, ovarian morphology, anti-inflammatory properties, and fertility

Obesity-associated melanocortin-4 receptor mutations are associated with changes in the brain response to food cues
