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There is little research around whether changing taste perception on the drugs works differently for sweetness from sugar and artificial sweeteners

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Cardiovascular and metabolic side effects should be observed particularly in patients with pre-existing conditions for safe administration

Theres no evidence that they have any sort of substantially lingering effect once you stop taking them, said Patrick ONeil, Ph.D., director of the MUSC Weight Management Center and a professor in the Department of Psychiatry and Behavioral Sciences