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Gastrointestinal side effects are common and can lead to treatment discontinuation, but they can be mitigated by gradual dose up-titration

On a $3,600 annual tirzepatide expense, that retroactive interest can exceed $1,000

10.1021/acs.jctc.1c00645 76 Van BaelenA

Their primary indication is the management of type 2 diabetes, where they are used alongside diet and exercise to improve glycaemic control by enhancing insulin secretion, suppressing glucagon, and supporting healthier glucose regulation 3 , 4