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The 25 to 30 day washout is the minimum for safe transition, and extending it slightly for those on higher tirzepatide doses is prudent risk management

Being off by just a few unit markings at the 20mg/ml concentration can mean a meaningful dose difference

Pregnancy also changes management: pregnant people with vaginal symptoms should consult a clinician before taking medications

This improvement has shown a decreased use of antihypertensive medications from baseline in the SURMOUNT-1 post hoc analysis [11] and an anticipated reduction in prescribed medication due to a 94% reduced risk of developing type 2 diabetes in adults with pre-diabetes and obesity or overweight [33]
