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Exogenous leptin administration is associated with a suppression of food intake, a reduction in body weight, and an upregulation of uncoupling protein 1 (UCP1) expression in adipose tissue depots, all of which have been suggested to require a fully functioning histaminergic system (79, 80, 92, 133)

Adjust food consistency as needed While this isnt always necessary, opting for soft or blended foods can improve digestive comfort

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