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Gene Therapies (Viral & Plasmid Vectors) Gene therapies attempt to permanently or semi-permanently alter the bodys production of myostatin or its natural antagonist, follistatin

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The CRISPR allele lag-1(oz536oz537) has the AID degron fused to the C-terminus of LAG-1, which is recognized by TIR1, resulting in germline-specific degradation of LAG-1