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It is becoming possible to imagine a future in which American regulators lose their grip on the safety and the efficacy of drugs

Patients should be encouraged to maintain an open line of communication with their healthcare providers, reporting any side effects or concerns that arise during their treatment

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BardetBiedl syndrome, a ciliopathy with autosomal recessive inheritance, is frequently associated with hyperphagia and obesity, in addition to syndromic features such as polydactyly, retinal dystrophy, and renal abnormalities [73]

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